Directory » JAMES CARSON
JAMES CARSON
Executive Director, Huffines Institute for Sports Medicine & Human Performance
Dr. Carson is a Professor in the Department of Kinesiology & Sports Management at Texas A&M University. He holds the Debbie & Mike Hilliard ’73 Endowed Huffines Institute Chair and is the Executive Director of the Huffines Institute for Sports Medicine and Human Performance. He is an exercise physiologist with molecular and cell biology training. He graduated from Akron St. Vincent & St. Mary High School and then received his B.S. in Business Administration and Ph.D. in Education with an emphasis in Exercise Physiology from The Ohio State University. At Ohio State, he was a 3-year varsity letterman in football and a Graduate Assistant Strength and Conditioning Coach with the Ohio State Athletic Department, where he worked with football, men’s and women’s basketball, and ice hockey teams. His training includes post-doctoral physiology and cell biology fellowships at the University of Texas Health Science Center-Houston and Baylor College of Medicine in Houston.
His research employs molecular biology techniques to examine skeletal muscle mass and metabolic regulation with cancer, regeneration from injury, and chronic inflammation conditions. Federal agencies have funded his research for over 20 years, and he has been an active collaborator on many funded projects with junior investigators. He has over 155 refereed publications related to muscle and exercise physiology, and his publications have received over 12,500 citations. He has 41 publications that have at least 100 citations. Mentorship in research has been a cornerstone of Dr. Carson’s career. His extensive research mentorship involvement includes junior and mid-career faculty and students from high school through the Ph.D. level. He has a long history of serving in leadership roles in doctoral education.
Dr. Carson has held academic leadership roles at the Associate Dean for Research and Department Chair levels. He also has considerable leadership experience in research centers and institutes related to colon cancer and tissue regeneration. He served as Senior Associate Dean for Research and Graduate Studies in the College of Health Professions at the University of Tennessee Health Science Center in Memphis (UTHSC). He also served as Executive Director of the Tennessee Institute for Regenerative Medicine. He has been a tenured Professor in the Department of Physical Therapy at UTHSC and the Department of Exercise Science at the Arnold School of Public Health at the University of South Carolina (USC). While on the faculty at USC, he served as Department Chair and the Associate Director for the Center for Colon Cancer Research at USC. Dr. Carson has substantial experience mentoring trainees and junior faculty at the department, college, and research center levels. He has been a regular grant review panel member for several federal funding agencies, including the NIH and Veterans Affairs. He is an Associate Editor for two journals. In his various administrative roles, he has been heavily involved in academic program growth, program restructuring, faculty recruitment, faculty mentorship, and student mentorship in research.
His research employs molecular biology techniques to examine skeletal muscle mass and metabolic regulation with cancer, regeneration from injury, and chronic inflammation conditions. Federal agencies have funded his research for over 20 years, and he has been an active collaborator on many funded projects with junior investigators. He has over 155 refereed publications related to muscle and exercise physiology, and his publications have received over 12,500 citations. He has 41 publications that have at least 100 citations. Mentorship in research has been a cornerstone of Dr. Carson’s career. His extensive research mentorship involvement includes junior and mid-career faculty and students from high school through the Ph.D. level. He has a long history of serving in leadership roles in doctoral education.
Dr. Carson has held academic leadership roles at the Associate Dean for Research and Department Chair levels. He also has considerable leadership experience in research centers and institutes related to colon cancer and tissue regeneration. He served as Senior Associate Dean for Research and Graduate Studies in the College of Health Professions at the University of Tennessee Health Science Center in Memphis (UTHSC). He also served as Executive Director of the Tennessee Institute for Regenerative Medicine. He has been a tenured Professor in the Department of Physical Therapy at UTHSC and the Department of Exercise Science at the Arnold School of Public Health at the University of South Carolina (USC). While on the faculty at USC, he served as Department Chair and the Associate Director for the Center for Colon Cancer Research at USC. Dr. Carson has substantial experience mentoring trainees and junior faculty at the department, college, and research center levels. He has been a regular grant review panel member for several federal funding agencies, including the NIH and Veterans Affairs. He is an Associate Editor for two journals. In his various administrative roles, he has been heavily involved in academic program growth, program restructuring, faculty recruitment, faculty mentorship, and student mentorship in research.
Education
Ph.D., Exercise Science, The Ohio State University
B.S., Business Administration, The Ohio State University
Diploma, Akron St. Vincent St Mary High School
COURSES TAUGHT
KINE 681. SEMINAR: EXERCISE PHYSIOLOGY
This course will introduce students to current research and topics relevant to the broad field of exercise physiology, with a primary focus on seminar-based presentations, reports, and discussions. Seminars will be provided by invited external and internal speakers. This course will also teach the scientific research process. Students who satisfactorily complete this course will attend presentations and participate in discussions of current research in exercise physiology. The student will learn skills for designing, conducting, analyzing and presenting research.
Spring 2025, Fall 2025
KINE 682. GRADUATE SEMINAR IN EXERCISE PHYSIOLOGY - SKELETAL MUSCLE RESPONSES TO ACUTE & CHRONIC EXERCISE
This course will introduce students to classic concepts and current research on topics pertinent to skeletal muscle responses to acute and chronic exercise, focusing on changes to muscle metabolism, structure, and function. The course will examine human and preclinical skeletal muscle responses to acute and chronic endurance and resistance exercise through a review of recently published literature and summary lectures. This course will also teach the scientific research process. The student completing this course satisfactorily will present and take part in discussions of current research in these exercise physiology areas. The student will learn skills for designing, conducting, and analyzing research.
Fall 2025
SELECTED PUBLICATIONS
Books and Monographs
Journal Articles
Counts BR*, Zhang Q*, Halle JL, Puppa MJ, Alway SE, Mohamed J, Loenneke JP, and
Carson JA+. The Effect of Cachexia on the Feeding Regulation of Skeletal Muscle Protein Synthesis in Tumor-Bearing Mice. J Cachexia Sarcopenia Muscle, in press July 2025. IF 9.1 [published with student]
Carson JA+. The Effect of Cachexia on the Feeding Regulation of Skeletal Muscle Protein Synthesis in Tumor-Bearing Mice. J Cachexia Sarcopenia Muscle, in press July 2025. IF 9.1 [published with student]
Joshi A, Xiao Z, Suman S, Cooper C, Ha K, Carson JA, Quarles LD, Smith JC, Gupta M. Structure-Based Design of Small-Molecule Inhibitors of Human Interleukin-6. Molecules. 2025 Jul 10;30(14):2919. doi: 10.3390/molecules30142919. PMID: 40733185. IF 5.0
Paez HG, Pitzer CR, Halle JL*, Ferrandi PJ, Carson JA, Mohamed JS, Alway SE. Impact of sarcopenia and obesity on skeletal muscle size, gene expression, and mitochondrial function. Geroscience. 2025 Jun 12. doi: 10.1007/s11357-025-01726-2. Epub ahead of print. PMID: 40504352. IF 6.2 [published with student]
Bullard BM, VanderVeen BN, Cardaci TD, Carson JA, Murphy EA. Mechanistic Insight into Physical Activity Pleiotropy in Cancer Prevention. Exerc Sport Mov. 2024 Fall;2(4):e00027. doi: 10.1249/esm.0000000000000027. PMID: 40443827; PMCID: PMC12121945. (invited refereed)
Cardaci TD, VanderVeen BN, Bullard BM, Carson JA, Murphy EA. Multisymptom Burden in Cancer Survivors: Benefits of Physical Activity. Exerc Sport Mov. 2024 Fall;2(4):e00029. doi: 10.1249/esm.0000000000000029. PMID: 40443828; PMCID: PMC12121944. (invited refereed)
Cardaci TD, VanderVeen BN, Huss AR, Bullard BM, Velazquez KT, Frizzell N, Carson JA, Price RL, Murphy EA. Decreased skeletal muscle intramyocellular lipid droplet-mitochondrial contact contributes to myosteatosis in cancer cachexia. Am J Physiol Cell Physiol. 2024 Jul 16. doi: 10.1152/ajpcell.00345.2024. Epub ahead of print. PMID: 39010842. IF 5.5
Zhan Q*, Halle JL*, Counts BR*, Pi M, Carson JA+. mTORC1 and BMP-Smad1/5 Regulation of Serum-Stimulated Myotube Hypertrophy: A Role for Autophagy. Am J Physiol Cell Physiol. 2024 Jul 1;327(1):C124-C139. doi: 10.1152/ajpcell.00237.2024. Epub 2024 May 20. PMID: 38766767. IF 5.5 [published with student]
Alway SE, Paez HG, Pitzer CR, Ferrandi PJ, Khan MM, Mohamed JS, Carson JA, Deschenes MR. Mitochondria transplant therapy improves regeneration and restoration of injured skeletal muscle. J Cachexia Sarcopenia Muscle. 2023 Feb;14(1):493-507. doi: 10.1002/jcsm.13153. Epub 2023 Jan 5. PMID: 36604839; PMCID: PMC9891964. IF 8.9
Chaib M, Holt JR, Fisher EL, Sipe LM, Bohm MS, Joseph SC, Simmons BW, Eugin Simon S, Yarbro JR, Tanveer U, Halle JL*, Carson JA, Hollingsworth TJ, Wei Q, Rathmell JC, Thomas PG, Hayes DN, Makowski L. Protein kinase C delta regulates mononuclear phagocytes and hinders response to immunotherapy in cancer. Sci Adv. 2023 Dec 22;9(51):eadd3231. doi: 10.1126/sciadv.add3231. PMID: 38134280; PMCID: PMC10745701. IF 15.4 [published with student]
Halle JL*, Counts BR*, Paez HG, Baumfalk DR, Zhang Q*, Mohamed JS, Glazer ES, Puppa MJ, Smuder AJ, Alway SE, Carson JA+. Recovery from FOLFOX Chemotherapy-induced Systemic and Skeletal Muscle Metabolic Dysfunction in Mice. Am J Physiol Endocrinol Metab. 2023 Aug 1;325(2):E132-E151. doi: 10.1152/ajpendo.00096.2023. Epub 2023 Jun 28. PMID: 37378624; PMCID: PMC10393342. IF 5.9 [published with student]
Halle JL*, Counts BR*, Quan Zhan*, James KM*1, Puppa MJ, Always SE, Carson JA+. Mouse Skeletal Muscle Adaptations to Different Durations of Treadmill Exercise After the Cessation of FOLFOX Chemotherapy. Front Physiol. 2023 Nov 1;14:1283674. doi: 10.3389/fphys.2023.1283674. PMID: 38028800; PMCID: PMC10648895. IF 4.0 [published with student]
Snoke DB, Bellefleur E, Rehman HT, Carson JA, Poynter ME, Dittus KL, Toth MJ. Skeletal muscle adaptations in patients with lung cancer: Longitudinal observations from the whole body to cellular level. J Cachexia Sarcopenia Muscle. 2023 Dec;14(6):2579-2590. doi: 10.1002/jcsm.13332. Epub 2023 Sep 19. PMID: 37727010; PMCID: PMC10751417
Book Chapters
Puppa M.J. and J.A. Carson. (2025). Chapter 12: Cancer Cachexia. In: Li Li Ji (ed) Springer Nature. The Skeletal Muscle: Plasticity, Degeneration and Epigenetics ISBN 978-3-031-88360-6
Conference Presentations
Center for Metabolic Health, UT Health San Antonio: “Skeletal Muscle Responsiveness in Cancer & Treatment”. Invited speaker, in person 5/22/25.
Inaugural Muscle Biology & Cachexia Conference, Houston Texas, Session: Mechanisms of Cancer Cachexia II, invited speaker in person, 05/20/25.
International Padua Days on Muscle and Mobility Medicine Conference, Padua Italy, invited speaker in person, Effects of exercise and chemotherapy in cancer cachexia. 3/26/25.
Texas Institute of Musculoskeletal Science Summit, Texas A&M University, Session: Neuromuscular Disease, invited speaker in person, 05/14/25.
Integrative Physiology of Exercise Conference by ACSM, Penn State University, Exercise & Cancer Session, invited featured speaker in person, 11/22/24.
16th International Conference on Cachexia, Sarcopenia and Muscle Wasting, Stockholm, Sweden, invited speaker in person, Session: The fat story of sarcopenia – the fat in muscle. 06/17/23.
2023 Oklahoma Geoscience Symposium, Oklahoma Nathan Shock Center on Aging, Gero-Oncology, invited plenary lecture. 4/4/2023.
OK Symposium on Pancreatic Cancer Cachexia. OU Health Stephenson Cancer Center. Oklahoma City, invited plenary lecture in person, 8/25/23.
18th International Biochemistry of Exercise Conference, Cancer and Exercise Symposium, Toronto, Canada. Invited speaker 5/28/22.